{"id":173085,"date":"2018-07-25T01:43:03","date_gmt":"2018-07-25T05:43:03","guid":{"rendered":"https:\/\/canadianinquirer.net\/v1\/?p=173085"},"modified":"2018-07-25T01:43:22","modified_gmt":"2018-07-25T05:43:22","slug":"genetics-researchers-eye-wrinkles-hair-loss-reversal","status":"publish","type":"post","link":"https:\/\/canadianinquirer.net\/v1\/2018\/07\/25\/genetics-researchers-eye-wrinkles-hair-loss-reversal\/","title":{"rendered":"Genetics researchers eye wrinkles, hair loss reversal"},"content":{"rendered":"
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WASHINGTON —<\/strong>\u00a0A research team from the United States has identified a gene in mice that can reverse wrinkles and hair loss and could be applied to humans in the future, local media reported.<\/div>\n
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“Wrinkled skin and hair loss are hallmarks of aging. What if they could be reversed?” genetic researchers from the University of Alabama at Birmingham (UAB) asked, saying they have made a breakthrough.<\/div>\n
In the study, mice were given an antibiotic that prompted changes in their gene.<\/div>\n
The antibiotic induced a mutation and the mice developed a wrinkled skin and underwent extensive hair loss in a matter of weeks. The mutation was caused by the mitochondria, small organelles in the cell that function like the cell’s digestive system, becoming dysfunctional.<\/div>\n
However, when the mitochondrial function was restored, the mice returned to smooth skin and a thick fur, indistinguishable from a healthy mouse of the same age.<\/div>\n
“To our knowledge, this observation is unprecedented,” said Keshav Singh, professor of genetics in the UAB School of Medicine.<\/div>\n
Singh said the mouse model should provide an opportunity for the development of preventive and therapeutic drug development strategies to augment mitochondrial functions for the treatment of aging-associated and other diseases.<\/div>\n
In humans, a decline in mitochondrial functions is seen during aging, and mitochondrial dysfunction can lead to age-related diseases. A depletion of the DNA in mitochondria is also associated with human mitochondrial diseases, cardiovascular diseases, diabetes, age-associated neurological disorders, and cancer.<\/div>\n","protected":false},"excerpt":{"rendered":"

WASHINGTON —\u00a0A research team from the United States has identified a gene in mice that can reverse wrinkles and hair …<\/p>\n","protected":false},"author":33,"featured_media":173090,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[37],"tags":[],"class_list":["post-173085","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","mauthors-philippine-news-agency"],"_links":{"self":[{"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/posts\/173085","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/users\/33"}],"replies":[{"embeddable":true,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/comments?post=173085"}],"version-history":[{"count":0,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/posts\/173085\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/media\/173090"}],"wp:attachment":[{"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/media?parent=173085"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/categories?post=173085"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/tags?post=173085"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}