{"id":130377,"date":"2017-11-11T04:26:50","date_gmt":"2017-11-11T09:26:50","guid":{"rendered":"https:\/\/canadianinquirer.net\/v1\/?p=130377"},"modified":"2017-11-11T04:26:50","modified_gmt":"2017-11-11T09:26:50","slug":"low-calorie-diet-may-help-reverse-type-2-diabetes-2","status":"publish","type":"post","link":"https:\/\/canadianinquirer.net\/v1\/2017\/11\/11\/low-calorie-diet-may-help-reverse-type-2-diabetes-2\/","title":{"rendered":"Low calorie diet may help reverse type 2 diabetes"},"content":{"rendered":"<figure id=\"attachment_130378\" aria-describedby=\"caption-attachment-130378\" style=\"width: 640px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/canadianinquirer.net\/v1\/wp-content\/uploads\/2017\/11\/5063259007_7712ae9cec_z.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-130378\" src=\"https:\/\/canadianinquirer.net\/v1\/wp-content\/uploads\/2017\/11\/5063259007_7712ae9cec_z.jpg\" alt=\"A US study released Thursday revealed how a very low-calorie diet can rapidly reverse type 2 diabetes in rats. (Photo by Mark Bonica\/Flickr, CC BY 2.0)\" width=\"640\" height=\"427\" srcset=\"https:\/\/canadianinquirer.net\/v1\/wp-content\/uploads\/2017\/11\/5063259007_7712ae9cec_z.jpg 640w, https:\/\/canadianinquirer.net\/v1\/wp-content\/uploads\/2017\/11\/5063259007_7712ae9cec_z-300x200.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><figcaption id=\"caption-attachment-130378\" class=\"wp-caption-text\">A US study released Thursday revealed how a very low-calorie diet can rapidly reverse type 2 diabetes in rats. (<a href=\"https:\/\/www.flickr.com\/photos\/23119666@N03\/5063259007\/in\/photolist-8Hqwv6-9zPHvt-64rac3-998D3r-9nAfqs-jvLxZ1-gMGJj-hBehep-5PJjy1-39cZGB-8xti27-pwbzqu-ejqCY6-4noQAx-8BGqoE-dN9J7f-7tb6Gw-3kMjcD-jYb6YN-aYbGbB-dN9FdJ-bXa6mD-9iUzzz-8uyVre-qZBn9-YSJ24T-YSJ2kV-nbSK5C-naWFAv-nbSK7G-Rdzcy1-nbSKah-Z9npJE-qZBuu-PiV5ya-7w7HMy\">Photo<\/a> by <a href=\"https:\/\/www.flickr.com\/photos\/23119666@N03\/\">Mark Bonica\/Flickr<\/a>, <a href=\"https:\/\/creativecommons.org\/licenses\/by\/2.0\/\">CC BY 2.0<\/a>)<\/figcaption><\/figure>\n<p>WASHINGTON\u00a0&#8212; A US study released Thursday revealed how a very low-calorie diet can rapidly reverse type 2 diabetes in rats.<\/p>\n<p>If confirmed in people, the insight provides potential new drug targets for treating this common chronic disease, said the researchers, according to the study published in the journal Cell Metabolism.<\/p>\n<p>In the study, a team led by the Yale University researchers showed three days of a very-low-calorie diet (VLCD), consisting of one-quarter the normal intake, lowered blood glucose and insulin concentrations in a rat model of type 2 diabetes without altering body weight.<\/p>\n<p>A track of the liver metabolic processes showed that it is due to a reduction in the conversion of lactate and amino acids into glucose and a reduction in the rate of liver glycogen conversion to glucose.<\/p>\n<p>Decreasing fat content, which in turn improves the liver&#8217;s response to insulin, also contributed to the VLCD&#8217;s positive effects.<\/p>\n<p>&#8220;We showed that it is a combination of three mechanisms that is responsible for the rapid reversal of hyperglycemia following a very low-calorie diet,&#8221; senior author Gerald Shulman, professor of the Yale University and an investigator at the Howard Hughes Medical Institute.<\/p>\n<p>The next step is to confirm whether the findings can be replicated in type 2 diabetic patients undergoing either bariatric surgery or consuming very low-calorie diets, the researchers said.<\/p>\n<p>Previous reports indicated that type 2 diabetes goes into remission in many patients who undergo bariatric weight-loss surgery, which significantly restricts caloric intake prior to clinically significant weight loss.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>WASHINGTON\u00a0&#8212; A US study released Thursday revealed how a very low-calorie diet can rapidly reverse type 2 diabetes in rats. &hellip;<\/p>\n","protected":false},"author":33,"featured_media":130378,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[37],"tags":[1890,32477,32478],"class_list":["post-130377","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-diabetes","tag-low-calorie-diet","tag-type-2","mauthors-xinhua","mauthors-philippine-news-agency"],"_links":{"self":[{"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/posts\/130377","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/users\/33"}],"replies":[{"embeddable":true,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/comments?post=130377"}],"version-history":[{"count":0,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/posts\/130377\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/media\/130378"}],"wp:attachment":[{"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/media?parent=130377"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/categories?post=130377"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/canadianinquirer.net\/v1\/wp-json\/wp\/v2\/tags?post=130377"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}